All of the coins have a face value of 100 lei. A majority of the coins are composed of silver, though occasionally, a gold coin is produced. The silver coins minted from 1996 to 2010 were all composed of .925 fine silver, but this was lifted to .999 fineness in 2011. The mass and diameter of the coins varies, and typically depends on the time it was produced and its composition. On the obverse, all bear the same design: the coat of arms of Moldova, with the value inscribed below, the year of minting above, and the state title (REPUBLICA MOLDOVA) to the sides. Each coin features a different reverse.
Two commemorative coins denominated in 100 lei were introduced in 2006. The first commemorated the 15th anniversary of the National Bank of Moldova, while the other commemorated the 15th anniversary of the Moldovan Declaration of Independence.
On November 12, 2007, the National Bank of Moldova issued another commemorative coin denominated in 100 lei. Belonging to the "Personalities" series, it commemorated the 480th anniversary of the accession of the throne to king Peter IV Rareș.
In 2008, two commemorative coins denominated in 100 lei were minted. Both belonged to the "Personalities" series. The first, which was silver, commemorated Antioh Cantemir, while the other, which was gold, commemorated Dimitrie Cantemir.
During 2011, four commemorative 100 lei coins were produced. The first, part of the "Ştefan cel Mare Central Park" series, commemorated Romanian Bogdan Petriceicu Hasdeu. For the "Historical Events" series, three coins were produced: one commemorating the 575th anniversary of the first record of Chişinău, another commemorating the 20th anniversary of the Moldovan Declaration, and the final one commemorating the 20th anniversary of the National Bank of Moldova.
The National Bank of Moldova issued two gold 100 leu coins on June 21, 2012. The first, part of the "Personalities" series, commemorated the 555th anniversary of the enthronement of Stephen the Great. Moldavian writer Ion Creangă was the subject of the second coin.